Consortium

HONGHE SENJU BIOLOGY CO. LTD - LUXI, YUNNAN PROVINCE, CHINA
Located in Yunnan province, Senju plant pyrethrum every year in Luxi county on the altitude 1600 to 2200 with ideal warm and humid climate and fertile soil for the pyrethrum growing. The company has already bred new cultivars with high yield and adopted the supercritical CO2 technology to extract high quality pyrethrins that the product economic index can reach the requirement for mass production, and the product of pyrethrins essential oil can reach 70% concentration.
Senju has carried out R&D programs resulting in pyrethrin based products to  prevent and control agriculture pests: for example, 5% pyrethrins emulsifiable concentrate, 1.5% pyrethrins Wettable power, 1.5% pyrethrins Micro-emulsion, 0.5% pyrethrins ultra-low-volume liquor, 0.5% pyrethrins granules. We also have other pyrethrins products to prevent and control pest in the room, such as 0.25%  Lvjian tianyuan mosquito repellent coil(type A), Lvjian tianyuan mosquito repellent coil(type C), 0.5% Lvjian tianyuan aerosol of killing pests and so on.Our company also has complete vendition system of Pyrethrum series products, and has established collaborative relation for a long time with America and Europe.

Tang Guoping (director); Wang Weimin (vice-director); Wang Dengju (lab head)
www.pyrethrum.com.cn  


PLANT RESEARCH INTERNATIONAL - WAGENINGEN UR – THE NETHERLANDS
Chemical Biology of Plant Compound Biosynthesis: a systems biology approach to biosynthetic pathways
This research programme focuses on characterizing and reconstructing biosynthetic pathways of secondary plant metabolites. The complexity of these pathways forces us to take an integrative, systems biology approach to fine tune the pathway and reach an optimal result. We use reverse engineering of existing pathways to develop an understanding of how plants optimize expression pathways.
Our main topics focus on metabolite induced insect resistance in plants by studying metabolic pathways leading to the production of insecticidal terpenoid and octadecanoid derivatives. For this purpose we study the plants Tanacetum cinerariaefolium (pyrethrum) and Persicaria hydropiper for the production of pyrethrins and polygodial. We carry out deep sequencing of ESTs from the relevant tissues producing these compounds and utilize various techniques such as RNAi in the host plant, heterologous expression in microbial hosts and overexpression in Arabidopsis, maize, tomato, pepper and chrysanthemum to characterize the genes found. A variety of analytical GC-MS and LC-MS tools are available to characterize the metabolite profile and to identify novel compounds. Insect assays with thrips and whitefly are regularly carried out to establish the effects of the changed metabolite profile on the insects. The final aim is synthetic biology: the ability to achieve controlled expression of a specific secondary metabolite in a plant host making use of systems biology tools.

The chemical biology group website 
Pyrethrum members: Maarten Jongsma, Liping Gao (postdoc), Ting Yang (PhD), Aldana Ramirez (PhD), Jing Mao (PhD), Tila Menzel (MSc), Geert Stoopen (technician)
PRI website

WUR website


HUAZHONG AGRICULTURAL UNIVERSITY – WUHAN, CHINA
To be added
CHINESE ACADEMY OF SCIENCES – KUNMING, CHINA
To be added
CHINESE AGRICULTURAL UNIVERSITY – BEIJING, CHINA
To be added